Roving eye pro1/8/2024 ![]() Ophthalmic manifestations may be the presenting feature of COVID-19 infection or they may develop several weeks after recovery. ![]() The viral ribonucleic acid (RNA) has been isolated from ocular tissues but the role of eye as a route for infection is yet to be substantiated. ![]() Direct effect due to virus, immune mediated tissue damage, activation of the coagulation cascade and prothrombotic state induced by the viral infection, the associated comorbidities and drugs used in the management are responsible for the findings in the eye. Conjunctivitis is the most common manifestation and can develop at any stage of the disease. 46 case reports, 8 case series, 11 cross sectional/cohort observational studies, 5 prospective interventional studies, 3 animal models/autopsy studies and 6 reviews/meta-analysis were included. Literature search was performed for the publications on ophthalmic manifestations of coronavirus disease-19 (COVID-19) between Januand January 31, 2021. This review was undertaken to help ophthalmologists recognize the possible manifestations and the stage of the viral disease when they commonly appear. Ophthalmologists world over are reporting various manifestations of the infection in the eye. It can affect almost every organ of the body. The infection can range from asymptomatic, mild to life threatening respiratory distress. The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had health implications of unprecedented magnitude.
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